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Activation of vagal afferent nerves has been observed after GLP-1 administration [34], whereas GLP-1 administration has been found not to suppress postprandial insulin secretion in patients with bilateral total subdiaphragmatic vagotomy and pyloroplasty [29]

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Roughly 12% of American adults now use GLP-1s, according to a recent Gallup survey
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The physiological mechanisms driving weight regain after semaglutide cessation are multifactorial

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