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Acetylation of -tubulin is tightly associated with the mobility of the cells

It is also known as a GI growth factor: it increases intestinal blood flow (Mayo et al

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Unfortunately, this synergy is lost in prolonged hyperglycaemic states due to selective dysfunction in GIP signallingdownregulation of GIPR mRNA and accelerated receptor degradationwhereas sensitivity to GLP-1 remains intact [22, 23]
