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In some cases, individuals have reported even higher weight loss with a consistent regimen, lifestyle changes, and medical supervision

Up to 55% of patients developed anti-drug antibodies [65], which were associated with systemic allergic reactions in approximately 5% of cases and injection-site hypersensitivity, including anaphylaxis, which necessitated early trial termination [66, 67]

In fact, some researchers are proposing that GLP-1 and related drugs are the most important drug-class breakthrough in medical history. 2 There is one simple but intriguing question about this whole topic: How can one drug have so many seemingly unrelated benefits

10.1056/NEJMoa1612917 36 HolstJ
[DOI] [PubMed] [Google Scholar] 4.Willms B, Werner J, Holst JJ, Orskov C, Creutzfeldt W, Nauck MA
