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Neuroprotective Mechanisms of GLP-1 Receptor Agonists Activation of Classical Signaling Pathways GLP-1 receptors belong to the Gs protein coupled receptor family

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As the primary counter-regulatory hormone to insulin, it collaborates with insulin to maintain glucose homeostasis (44)

doi: 10.1152/ajpcell.00093.2016

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The recent positive topline results from Eli Lilly and Company 's ATTAIN-MAINTAIN trial for orforglipron, however, signal a potential paradigm shift