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Real-world effectiveness studies support these clinical trial findings

But for folks living with type 2 diabetes, keeping blood sugars under good control can help prevent severe vision loss, and even slow progression of retinopathy

In summary, the relatively higher expression of GLP-1R on -cells allows GLP-1 to indirectly inhibit glucagon secretion by promoting somatostatin secretion

Exendin-4, a GLP-1RA, upregulated hepatic ABCA1 via the CaMKK/CaMKIV/PREB pathway and alleviated fatty liver in HFD-fed mice [39]

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