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(Lausanne) 12 , 763646 (2021)

doi: 10.1016/j.diabet.2025.101641

While the mechanism underlying the diminished insulin response to GIP in T2D has not yet been fully elucidated, receptor downregulation (55) and desensitization (56) have been suggested as potential causes

When labs are used, they are most commonly checked at the start of care and repeated three to six months later to assess tolerance, safety, or metabolic changes
Weight loss has long been a cornerstone of preventive health yet for many people, traditional strategies like diet and exercise alone don't deliver lasting results

2019 ESC guidelines on dia- betes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD
