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How This Works 5-Amino-1MQ (5-amino-1-methylquinolinium) is a synthetic small molecule not a peptide that selectively inhibits nicotinamide N-methyltransferase (NNMT) [1]
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2024;12(2):e12278
No other adverse developmental outcomes were observed in animal reproduction studies with nirmatrelvir at systemic exposures (AUC) greater than or equal to 3 times higher than clinical exposure at the approved human dose of PAXLOVID (see Data)
Ghosh-Swaby OR, Goodman SG, Leiter LA, Cheng A, Connelly KA, Fitchett D, Jni P, Farkouh ME, Udell JA
