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Recommended Timeline for GLP-1 Discontinuation Before Conception Most fertility specialists and reproductive endocrinologists recommend stopping GLP-1 medications like compounded semaglutide at least 2-3 months before attempting conception

doi: 10.1177/2040622315609312 [DOI] [PMC free article] [PubMed] [Google Scholar] 59

Lancet Gastroenterol Hepatol 2024

Anyone considering a GLP-1 drug should talk with both their primary care or obesity medicine doctor and their neurologist, says Ali

At 10 mg/mL, 5 mg equals 50 units

Meanwhile, ahead of its recent approval by the FDA, Eli Lilly's tirzepatide showed a 20.9% weight reduction at 72 weeks compared with 3.1% reduction with the placebo in the SURMOUNT-1 trial [37]
