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Rajesh Kumar, head of European life sciences and healthcare equity research with HSBC, and colleagues upgraded the firms rating on Lilly shares from Reduce to Hold, citing what it called greater clarity on the commercial potential of orforglipron

Nunns M, et al

A study published last month in the Journal of the American Medical Association found that bariatric surgery is associated with a favorable ratio of fat loss

Burak Altintas, MD, an orthopedist with UTMB, who was not involved in this study, further highlighted the following limitations of the research: The limitations include retrospective design and likely residual confounding despite matching as fracture risk is influenced by many variables that are not reported [] Further, the comparison group is heterogeneous, combining another GLP-1 receptor agonist (dulaglutide) with two mechanistically different weight-loss medications

Eli Lilly, which makes reatrutide and Zepbound, hasn't even submitted the trial results yet to the FDA for approval