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The new coverage could unlock millions of potential patients for Novo and Lilly, intensifying their competition in the obesity market

AP events were predominantly reported for unknown indications (53.8%) and T2DM (43.0%)

The choice will depend on patient preference for oral versus injectable administration, the importance of cardiovascular outcomes data, and the weight loss goals of the individual patient

The dispute centers on pharmaceutical compounding, which is legal for individualized patient needs, and whether it crossed into large-scale marketing

Saxenda a higher-dose daily liraglutide formulation Wegovy a higher-dose weekly semaglutide formulation Zepbound the weight-loss formulation of tirzepatide These medications are typically approved for adults with obesity, or for those who are overweight with additional health conditions such as high blood pressure, abnormal cholesterol, or sleep apnoea

The most frequently reported clinical outcomes included initial hospitalization or prolonged hospitalization (13.6%) and other serious medical events (12.3%)