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OH NO OZEMPIC: How GLP-1 RAs May Be Slimming Down Your Oral Health Aug 3, 2025 8 min read Updated: Sep 10, 2025 Sooyun Christina Kim, Amreet Minhas, Beatrice Sixt Project Smile Global August 3, 2025 In recent years, Ozempic, a medication used to treat type 2 diabetes mellitus (T2DM), has increased in popularity (Callaghan et al

By entering the subcutaneous fat layer, nearly 90% of the medication becomes bioavailable, leading to more predictable levels in the bloodstream

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Additionally, tirzepatide is not recommended for people with severe gastrointestinal issues like gastroparesis

Nonetheless, the net effect from the meta-analysis supports the combined therapy, although it exhibits considerable heterogeneity and includes very few studies