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Many people are willing to push past discomfort if they believe the treatment will help them achieve meaningful results

This directly impacts how many units you need to draw for your 2mg dose

There is an important nuance here

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"And because [berberine] is sold as a dietary supplement, FDA approval is not required." Any effects berberine might have on weight are far smaller than you'd get from weight loss medications

The best current explanation ties it to the glucagon receptor activity, which is the same component driving the extra fat loss