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Description
GLP-1 medications can suppress appetite and worsen gastrointestinal symptoms, increasing the risk of malnutrition or sarcopenia issues already prevalent in older CKD patients

AlkaLean Fast Facts Product: AlkaLean dietary supplement capsules Brand: Alkalean Research (alkaleann.com) Format: Vegetarian capsule (hypromellose shell) Serving size: 1 capsule per day Servings per container: 30 (30-day supply) Active ingredient 1: Chicory Root Inulin ( Cichorium intybus root) - 211 mg Active ingredient 2: Potato Resistant Starch (tuber) - 100 mg Active ingredient 3: Probiotic Blend - 35 mg total ( Bifidobacterium infantis , Clostridium butyricum , Akkermansia muciniphila ) CFU count per strain: Not disclosed on label - contact brand directly Other ingredients: Hypromellose, microcrystalline cellulose, magnesium stearate, silica Primary mechanism: Prebiotic fiber fermentation to SCFA production to gut L-cell GLP-1 stimulation Finished-product clinical trials: None identified FDA status: Not FDA-approved

pmid:37003572 4

SURMOUNT-5 trial: 8.3% mean weight loss Glapp users: 10.1% mean weight loss Relative improvement: +21.7% The Broader Scientific Conversation Our findings dont exist in isolation

One innovative therapy we offer involves GLP-1 receptor agonists, such as Ozempic, to effectively support patients in managing type 2 diabetes and achieving their weight-loss goals

Elkind-Hirsch K, Marrioneaux O, Bhushan M, et al
