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Investigated for energy expenditure and thermogenic activity
This analytical review critically examines the evidence surrounding GLP-1 agonists efficacy, safety, and real-world implications for obesity treatment in individuals without diabetes
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After adjustment for sex, BMI, hsCRP, and sCD163, semaglutide significantly decreased epigenetic aging: PCGrimAge (-3.1 years, P = 0.007), GrimAge V1 (-1.4 years, P = 0.02), GrimAge V2 (-2.3 years, P = 0.009), PhenoAge (-4.9 years, P = 0.004), and DunedinPACE (-0.09 units, 9 % slower pace, P = 0.01)
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Trulicity vs Zepbound: Zepbound delivers 21% weight loss vs Trulicity's 4-7% with dual GIP/GLP-1 action
