tirzepatide gout and change in uric acid and its association with weight reduction: post hoc analyses of the SURMOUNT-1 randomised placebo-controlled trial Easing the Pain of Gout:

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We also included markers of diabetes severity, including duration (in years [continuous]), complications (yes vs no), hemoglobin A 1c value (continuous), and use (yes vs no) and duration (in years [continuous]) of diabetes medications (metformin, insulin, sulfonylureas, or glitazones)

[DOI] [PubMed] [Google Scholar] 738.Hollander P, Gupta AK, Plodkowski R, et al

doi:10.1177/15563316251355551 Achilleos K, Petrou C, Nicolaidou V, Sarigiannis Y

Medication should generally be considered as an adjunct to, not a replacement for, psychological treatment