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Patients experiencing recurrent or increasingly severe injection site reactions with each dose should schedule a non-urgent appointment with their healthcare provider or diabetes educator
Only a licensed clinician may prescribe this drug for this condition if in their clinical judgment use of the product is medically appropriate

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Obesity is commonly the outcome, which reduces the efficiency of exogenous leptin as a therapeutic agent

doi: 10.3389/fendo.2017.00098 Received 18 January 2017 Accepted 18 April 2017 Published 03 May 2017 Volume 8 - 2017 Edited by Maria Felicia Faienza, Universit degli studi di Bari Aldo Moro, Italy Reviewed by Jameela Banu, University of Texas Rio Grande Valley, USA