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Possible role of GLP-1 in antidepressant effects of metformin and exercise in CUMS mice

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GLP-1 RAs can also cause bloating and burping, partly from delayed stomach emptying (food sits and ferments longer in the gut) and perhaps changes in gut bacteria
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Mood changes and anxiety are possible side effects of GLP-1 receptor agonists

4- Non-motor symptoms like constipation, depression, sleep and cognition remain major unmet needs in Parkinsons care

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