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Pharmacology, Physiology, and Mechanisms of Incretin Hormone Action

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A practical approach is to fill half your plate with vegetables, one quarter with lean protein, and one quarter with a whole grain or healthy fat

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Research from the Journal of Clinical Investigation shows tirzepatide binds the GIP receptor with affinity similar to native GIP (Ki of 0.135), while its GLP-1 receptor affinity is roughly five-fold weaker than native GLP-1 (Ki of 4.23)

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