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Diabetes Obes Metab (2021) 23(3):75462

Final Takeaway Whether GLP-1 medication is used or not, long-term metabolic health depends on one foundation : A resilient microbiome healthy SCFAs stable GLP-1 lasting metabolic balance

While traditional GLP-1 agonists activate only GLP-1 receptors, tirzepatide also stimulates GIP receptors

Pharmacology professor Jamie Alan of Michigan State University referred to them as rebranded, older weight-loss products with no scientific proof that they mimic prescription GLP-1 drugs

A systematic review of 17 reviews conducted in 2022 found that a majority of the studies (twelve) reported modest weight loss between 1.36 kg (95% CI: 2.51 to 0.21) to 3.8 kg (95% CI: 5.6 to 1.9) for breast cancer patients participating in multicomponent behavioral intervention studies [31, 32]

While this may limit the generalizability of the studys outcomes to a certain degree, the overall trend remained consistent across all racial and ethnic groups