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This was because in contrast to mammals where the islets of Langerhans are embedded in the exocrine pancreas, in fish, the islets reside in a separate organ known as Brockman bodies, thus providing an enriched source of glucagon-producing cells

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Bray GA, Heisel WE, Afshin A, et al

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487 Question 7: How should retinopathy be managed in persons with DM

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