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Exenatide for weight-loss maintenance in adolescents with severe obesity: A randomized, placebo-controlled trial

One study found that nutrient-induced GLP-1 response was one of the best predictors of T2DM remission after RYGB (32), whereas another study found that GLP-1 response to a mixed meal in patients 2 years after VSG was similar regardless of postoperative remission, relapse, or no remission of T2DM (83)

Or they may require you to try multiple cheaper drugs first to make sure something more affordable doesn't do the trick (this is called step therapy)

The Dose-Response Question: Yes, higher doses produce more dramatic effects

3,4 GLP-1RAs mimic the action of endogenous GLP-1, activating GLP-1R, thereby enhancing insulin secretion, inhibiting glucagon release, delaying gastric emptying, and reducing food intake through central appetite suppression

If more than five days have passed, skip the missed dose and wait for your next scheduled injection