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Semaglutide, the active ingredient in brand medicines like Ozempic and Wegovy, could raise the risk of a relatively rare eye disease that is a leading cause of vision loss, according to a retrospective study.

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In this Review, Moheet and colleagues describe these conditions, with particular emphasis on the effects of CFTR modulator therapy, as well as the challenges related to ageing in people with cystic fibrosis.

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GLP-1 medications interact with certain drugs, supplements, and substances that may reduce efficacy or increase side effects