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In considering which interventions under study for preventing and/or treating AD/ADRD show promise, the committee identified the following three categories of interventions based on different endpoints of relevance

Insulin resistancewhen cells become less responsive to insulinaffects approximately 38% of US adults with prediabetes and represents a critical pathway to type 2 diabetes and cardiovascular disease

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Azar stressed that some patients can maintain part of their weight loss by adopting healthy lifestyle habits, such as eating whole foods, prioritizing protein, and staying physically active