can semaglutide cause missed periods and Periods: What You Need to Know Can GLP-1s Change Your Period?

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### Funding Statement SDL and AC were supported by the National Science Foundation (Grant Nos.\ CAREER DMS-1944574 and DMS-2325258) ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained

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Sacubitril/valsartan has demonstrated consistent benefits not only in HF with reduced ejection fraction (HFrEF) but also in selected patients with mildly reduced or preserved ejection fraction (HFmrEF/HFpEF), especially women and those with borderline left ventricular ejection fraction, as shown in the Prospective Comparison of ARNI with ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure (PARADIGM-HF) and Prospective Comparison of ARNI with ARB Global Outcomes in HF With Preserved Ejection Fraction (PARAGON-HF) trials and supported by Indian ARNI PRESERVED study