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Metformin is FDA-approved for type 2 diabetes and is sometimes prescribed off-label as part of weight management approaches

Notably, GLP-2 also rapidly increased nutrient absorption in normal rodents (64) and in animals with surgical gut resection mimicking SBS (65)

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Additionally, patients with T2DM and comorbid cardiovascular or chronic kidney disease who received once-daily oral semaglutide (14 mg) exhibited a cardiovascular safety profile similar to that of the subcutaneous form [49]

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