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Vitamin B12 injections have been useful in correcting specific deficiencies and in boosting energy and cognition, while GLP-1 agonists appear to have a much broader effect on healthspan extension via their diverse metabolic and neuroprotective attributes

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Over 32 weeks, CagriSema produced HbA1c reductions of 2.2 percentage points compared to 1.8 with semaglutide alone and 0.9 with cagrilintide alone, with CagriSema statistically superior to cagrilintide

Semaglutide has been used since 2017 for managing type 2 diabetes (under the brand name Ozempic) and more recently, since 2021, for weight loss (as Wegovy)

Hofbauer LC, Witvrouw R, Varga Z, Shiota N, Cremer M, Tanko LB, et al