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Purpose of Review: This article summarizes the medical management of obesity with an emphasis on incretin-based therapeutics that target the neuro-hormonal basis of obesity.Recent Findings: Medications that mimic the effect of incretins, a group of peptide hormones released in response to nutrient intake that regulate appetite, result in potent and durable weight loss

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Studies have linked GLP-1 medications to various eye conditions, some of which may lead to vision loss

Learn what to eat on semaglutide, which supplements may help, and how lab testing can personalize treatment and support healthy, sustainable weight loss.

GLP-1 receptor agonists are a type of non-insulin medication used to treat type 2 diabetes

In earlier studies, retatrutide reduced liver fat by more than 80% in people with metabolic fatty liver disease, with most participants no longer meeting diagnostic thresholds