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[8] Metformin with GLP-RA & Long-term Outcomes: In patients with T2D, dual therapy with metformin and GLP-RA has demonstrated a 39% lower incidence of adiposity-related cancers (HR 0.61) and a 67% reduction in all-cause mortality (HR 0.33) compared to DPP-4 inhibitor use, with effects most pronounced in younger people with obesity

For people with IBD like Crohns disease or ulcerative colitis (UC) research suggests the drug may help by reducing swelling in the gut and helping the lining of the intestines heal

This means the hair loss correlates more strongly with the amount and speed of weight lost than with which specific medication caused it

The most commercially significant event in the GLP-1 market in 2026 is the opening of the generic semaglutide window

Why Traditional Dieting Is So Hard Traditional weight loss plans rely heavily on calorie restriction and willpower