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Bottom line: Fiber-forward, prebiotic approaches appear to be the most reliable microbiome-based strategy for managing metabolic disease

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These renal benefits are thought to be mediated by mechanisms including reduced glomerular hyperfiltration, enhanced natriuresis, and systemic anti-inflammatory effects

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Compounded semaglutide is not FDA-approved, and this blog does not constitute medical advice

71 SURPASS-3 (ClinicalTrials.gov identifier: NCT03882970): assesses efficacy and safety of tirzepatide versus insulin degludec in patients with T2D prescribed metformin with or without SGLT2 inhibitors