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Based on your health screening, your medication may include supportive supplements (like B6 or B12) , as selected by your prescriber

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People expect that I should never take a medication or use a medication

It is possible that both hypotheses are true, and that EECs are the cells responsible for visceral pain modulation, but that the mediator of this interaction with peripheral nociceptors is extracellular (or even synaptic) cGMP