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The most common designs are observational studies

I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance)

We also address current barriers to implementation and evidence-based use, ongoing clinical trials, and future directions, including combination therapies that may enhance efficacy and patient outcomes.

DPP-4 inhibitors were introduced for the treatment of type 2 diabetes in 2006

While these agents are not recommended during pregnancy, their use in the preconception, periconception, and postpartum periods is increasing