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The relationship remained consistent after adjustment for study duration, baseline body mass index, sex distribution and diabetes status, at 0.36 millimetres of mercury per one per cent weight loss

The population who switched were made up of a higher percentage of people in the 45-64 age range, female, white, not Hispanic or Latino, those with overweight/obesity, T2D, and those who initiated treatment before 2021

More importantly, the type of evidence is different

Risk of Gastrointestinal Adverse Events Associated With Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss, October 2023, Sodhi et al

For patients seeking insurance coverage, pre-documenting a 6-month log of lifestyle interventions, such as diet and exercise, can align with major payer criteria and raise first-pass approval likelihood to as high as 90% in compliant cases , according to this payer-focused review

Campos RV, Lee YC, Drucker DJ