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However, they are typically recommended as part of a comprehensive weight management plan that includes a healthy diet and regular physical activity

Diagnostics (Basel, Switzerland) 15 , 580 (2025)

Experts recommend precision nutrition strategies: Smaller, nutrient-dense meals rich in high-quality protein Micronutrient support for vitamins B12, D, folate, magnesium and iron Hydration solutions to counter reduced thirst signals Fiber and probiotics to support gut health GLP-1 therapies are revolutionizing obesity and diabetes care, but they also reshape physiology in ways that demand attention

Quite similar results, although of lesser extent and for lesser outcomes, have been observed with GLP-1RA [29]

These mechanisms make GLP-1 agonists particularly effective in managing T2D and promoting significant weight loss

Although proven effective, GLP-1 RAs have been associated with numerous GI adverse events