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Mixed-nutrient meals higher in protein or fiber and specific dietary patterns (e.g., Mediterranean diet) may also increase GLP-1 secretion

4 This led to the FDA-mandated warning label for GLP-1RAs to include the risk of DR progression, raising questions for patients and ophthalmologists alike about the safety of this class of medication

Fiber intake Soluble fiber gets fermented by gut bacteria into short-chain fatty acids, particularly butyrate, which directly stimulates GLP-1 secretion from intestinal L-cells

A baby who nurses once daily and eats solid foods for the other meals has minimal breast milk exposure

Invasive Hemodynamics At the study endpoint, rats were anesthetized with 3% isoflurane until unresponsive

Persistent diarrhea on GLP-1 can come from bile acid malabsorption, which causes watery, urgent stools often in the morning or soon after eating