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The Transportation Security Administration (TSA) permits passengers to carry injectable medications, including Zepbound (tirzepatide), in both carry-on and checked baggage

Zepbound typically requires several months of dose escalation to reach therapeutic levels, with more pronounced weight loss effects occurring at maintenance doses of 5-15 mg weekly

This is a delicate process because the peptide molecules in tirzepatide can be fragile

Even if you were on 15 mg tirzepatide, you will begin at the lowest semaglutide dose to allow your body to adjust to the different receptor mechanism

In major clinical trials, participants lost about 5% of their starting body weight in the first 12 weeks, with continued progress for 6 months to a year

The resulting emotional exhaustion can manifest as physical tiredness