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This effect appeared to be mediated by antioxidant mechanisms involving GSK3 phosphorylation 156 , and it was also associated with a reduction of measures of memory impairment in mice 157

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This hormone plays a critical role in appetite regulation by slowing down the digestion process, helping people feel full sooner and longer, and eat fewer calories overall

Long-term efficacy and safety of linagliptin in patients with type 2 diabetes and severe renal impairment: a 1-year, randomized, double-blind, placebo-controlled study

Further stratification by obesity class, duration of GLP-1 use, and interval between discontinuation and conception would also strengthen causal interpretation
