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This increases insulin secretion when blood sugar levels go up, leading to better blood sugar management

The result is a medication that progressively loses its ability to bind receptors and produce the effects you need for weight management and metabolic health

Weight loss velocity naturally decreases over time, following a logarithmic rather than linear pattern

However, the better medication for an individual depends on more than average weight loss

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If you are in your first four weeks on a new dose, the wearing-off effect is expected and temporary