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The PNA mouse may be the best animal model of polycystic ovary syndrome
Regular provider check-ins during the first 3 months establish a safety baseline, monitor for adverse events, and adjust dosing as needed
In the central nervous system, pre-proglucagon and hence GLP-1, GLP-2 and OXM are exclusively found in a small population of nerve cells in the nucleus of the solitary tract
Relevant literature includes pharmacodynamic studies, gastric motility investigations, endoscopic findings, perioperative observational studies, anesthesia-related case reports, and emerging population-level outcome data
10.1016/j.neuropharm.2017.12.007 Neuropharmacology 72 ZhangH.ChuY.ZhengH.WangJ.SongB.SunY
Neeland IJ, Linge J, Birkenfeld AL
