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There is an urgent need for therapies that address multiple aspects of this cardiometabolic syndrome, such as improving blood glucose levels, reducing body weight, and mitigating cardiovascular risk [4,5]

For men specifically, the visceral fat reduction advantage of tirzepatide is particularly relevant

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[53] Tirzepatide's efficacy for chronic weight management (weight reduction and maintenance) in combination with a reduced-calorie diet and increased physical activity was established in two randomized, double-blind, placebo-controlled trials in adults with obesity or overweight who had at least one weight-related condition