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British Journal of Pharmacology, 178(S1), S27S156

Hence, this leads these hormones to work for a longer time, and as a consequence, pancreatic -cells become more sensitive to increases in blood glucose, causing the release of insulin and a decrease in glucagon

For people already using a closed-loop system, that is a meaningful step forward
Dipeptidyl peptidase-4 (DPP-4) inhibitors, also known as gliptins, are used in the management of type 2 diabetes

In practice, physical dependence at prescribed doses is rare
