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No serious adverse effects, such as hypoglycemia, have been observed when using this kind of insulin in patients with cirrhosis.87 Liver transplantation Liver transplantation quickly normalizes glucose tolerance and insulin sensitivity in hepatogenous diabetes

Patients new to self-injection typically experience slightly higher bruising rates initially, with improvement as technique improves over time

TROA has support from ICER and several obesity advocacy organizations, but drug cost is a significant barrier to passage [15,16]

The drug-induced glucose-dependent insulin secretion and glucagon suppression lead to the loss of exogenous GLP-1 signaling and weight regain
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Accessed January 22, 2026
