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In addition, in the EMPEROR-reduced trial, enrolling about 3700 patients affected by heart failure with reduced ejection fraction (HFrEF), empagliflozin significantly reduced the risk of heart failure hospitalization and decreased total hospitalization for HF regardless of the presence of diabetes or baseline levels of glycohemoglobin (HbA1c) (49, 50)

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"There are now effective drugs, and this could lead to higher labor productivity, gains in longevity, and potentially reduce medical costs costs elsewhere in the health system." Columbia Threadneedle Investments reported that the weight-loss drug industry could become a $1.7 trillion annual market if 100 million Americans took GLP-1s at their current price

These treatments have gained FDA approval for use in adults struggling with obesity or overweight conditions linked to health risks

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