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At the onset of behavioral testing, all experimental mice were acclimatized to the behavioral testing room for 30 minutes prior to the commencement of the experiments, during which a white noise generator was activated to facilitate adaptation to the testing environment

10.1136/bmj.g2646 14 DruckerD

Rapid weight reduction can signal energy deficit to the hypothalamus, potentially suppressing gonadotropin-releasing hormone (GnRH) pulsatility

Diabetes Obes Metab 2023

Patients treated with Mounjaro achieved an average weight loss of 20% over 84 weeks, with some individuals experiencing even greater weight loss