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Explore how GLP1 therapies can improve MASLD even in nonobese, nondiabetic patients and refine liverfirst treatment strategies.

Cardiovascular disease (CVD) is the main cause of death and disability among people with type 2 diabetes.[2] Adults with type 2 diabetes are two to four times more likely to develop CVD than adults without diabetes.[3] The FDA's decision on semaglutide is based on results from the SUSTAIN 6 cardiovascular outcomes trial (CVOT), which examined the cardiovascular safety of adding Ozempic or placebo to standard-of-care in adults with type 2 diabetes and established cardiovascular disease

Non-obese diabetic mice aged 7 weeks were treated for 1 week with JD-5037, then euthanised

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