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GLP-1s often work better for both goals

Finally, our in vitro results indicated that liraglutide may attenuate cartilage degradation through an anti-catabolic effect at both at the protein and gene expression levels

D., Klammt, S., Posch, M

Some insurers wont cover either drug without prior authorization from a doctor

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This phase 3b trial evaluates mirikizumab combined with tirzepatide versus mirikizumab with a placebo in adult participants with moderately to severely active CD and comorbid obesity (111)
