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doi: 10.1016/j.ebiom.2024.105284

Holst, J.J

The plotter shows in concrete visual terms that a microdose at steady state achieves concentrations that a standard dose produces within its first week

Cardiovascular benefit for GLP-1RAs was shown in 2016 for liraglutide in the LEADER trial and semaglutide in the SUSTAIN 6 trial

Studies show that GLP-1s decrease pain/stiffness, protect cartilage, and improve mobility, possibly preventing surgery for some

It belongs to a class of medications called glucagon-like peptide-1 (GLP-1) receptor agonists , which work by mimicking a natural hormone that regulates appetite and food intake