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OCLC 1429657918

30 The present data suggest that among patients with MASLD, GLP-1 RAs may offer other survival benefits than those conferred by slowing the risk of liver disease progression

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To optimize effective absorption, patients are required to adhere to complicated dosing conditions of taking the drug in a fasting state (at least 30 minutes before any food intake) with no more than 4 ounces (approximately 120 mL) of plain water

The most common examples include a 12-hour daily fast and a 16-hour daily fast

In the LEADER trial (Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results), researchers found that liraglutide reduced the risk of cardiovascular events in diabetic patients, including heart attack, stroke, and cardiovascular death, by 13% compared to placebo