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GLP-1 receptor agonists mimic a hormone your body already produces called glucagon-like peptide-1

The mechanisms underlying its weight-reducing effects are not fully understood but may involve enhanced hypothalamic expression of anorexigenic neuropeptides, including proopiomelanocortin POMC, corticotropin-releasing hormone CRH, and thyrotropin-releasing hormone TRH, possibly modulating the POMC/melanocortin-4 receptor (MC4R) pathway [21]

Liou Frontiers in Physiology.2026;[Epub] CrossRef Laser-Evoked Potentials in the Early Diagnosis of Diabetic Neuropathy and Their Association with Cardiovascular Autonomic Reflex Tests: A Retrospective Observational Study in Patients with Type 2 Diabetes Giovanni Umberto Borin, Marta Aventaggiato, Cristina Bittante, Vittorio Cacciatori, Alessia Segatti, Elisa Concon, Grazia Devigili, Enzo Bonora, Giacomo Zoppini, Giovanna Maddalena Squintani Brain Sciences.2026

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References Obesity and overweight [Online]

What matters now is monitoring, not guilt
