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Managing these conditions effectively at an early stage with pharmaceutical interventions could lead to a decrease in the need for more aggressive treatments and hospitalizations in the long run, thereby saving healthcare costs

Lacy BE, et al

11.3 The Central Risk Variable: Intake Quality The most important determinant of nutritional adequacy during GLP-1 therapy is not the medication itself

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At the end of the original 72-week study, people on the highest dose of either medication were randomized into two arms: the treatment group taking a once-daily dose of orforglipron and a placebo control group