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TIPO-1 (Phase 2b, published in The Lancet , 2008)

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Briefly, in this a double-blind (patient and investigator) study, participants (aged 1875 years) had type 2 diabetes for 6 months or longer (HbA1c 7.0%10.5%), which was inadequately controlled with diet and exercise alone or with stable metformin therapy, and a body mass index of 2350 kg/m 2 (18)